Patent applications which contain disclosures of nucleotide and/or amino acid sequences must contain a listing of the sequences in a specified format. If a review of the patent application reveals that the format rules have not been complied with by the applicant, he/she will be sent a notice detailing the deficiency and given a period of at least 1 month for response. It is important to note that the response cannot contain any "new matter." Therefore, the application as filed must provide adequate support for any information supplied later in order to comply with the sequence listing format rules.